Which two gonadotropins are most commonly assessed together as part of fertility evaluation?

• A. FSH and LH
• B. FSH and Prolactin
• C. LH and TSH
• D. FSH and hCG

Answer: (A)

The two pituitary hormones that regulate the ovaries—FSH and LH—are routinely measured together in fertility evaluation because they directly drive follicle growth, estrogen production, ovulation, and the luteal phase. FSH stimulates developing follicles and helps establish the early follicular environment, while LH triggers the mid-cycle ovulatory surge and supports the corpus luteum after ovulation. Checking both provides a clear picture of how the hypothalamic-pituitary-ovarian axis is functioning and helps assess ovarian reserve and ovulatory capability. Prolactin and TSH are not gonadotropins and serve different regulatory roles, and hCG is a pregnancy-related or ovulation-inducing hormone rather than a standard gonadotropin measured in this context.