Which tube type is used to obtain serum after clotting?

Prepare for the Clinical Chemistry Numericals Test. Study with comprehensive questions, each with detailed explanations. Boost your confidence and excel on your exam!

Multiple Choice

Which tube type is used to obtain serum after clotting?

Explanation:
To get serum, you allow the blood to clot and then separate the liquid from the clot by centrifugation. The clotting factors (like fibrinogen) are consumed to form the clot, so the liquid portion that remains is serum, which lacks these clotting factors. Therefore the tube used is a serum tube, designed without anticoagulants to promote clotting (often red-top or serum separator tubes). In contrast, tubes containing anticoagulants such as EDTA, heparin, or citrate prevent clotting, so they yield plasma after centrifugation rather than serum.

To get serum, you allow the blood to clot and then separate the liquid from the clot by centrifugation. The clotting factors (like fibrinogen) are consumed to form the clot, so the liquid portion that remains is serum, which lacks these clotting factors. Therefore the tube used is a serum tube, designed without anticoagulants to promote clotting (often red-top or serum separator tubes).

In contrast, tubes containing anticoagulants such as EDTA, heparin, or citrate prevent clotting, so they yield plasma after centrifugation rather than serum.

Subscribe

Get the latest from Passetra

You can unsubscribe at any time. Read our privacy policy