Which substance is most commonly abused worldwide?

• A. Ethanol
• B. Methanol
• C. Isopropanol
• D. Acetone

Answer: (A)

Ethanol is the most commonly abused worldwide because it is the psychoactive component in alcoholic beverages, legally available, culturally integrated, and widely socially accepted. People can access it in beer, wine, and spirits almost anywhere, which drives its extensive and common pattern of use. In contrast, methanol, isopropanol, and acetone are mainly solvents or industrial chemicals that are highly toxic if ingested and are not used recreationally on a global scale. Their abuse would be rare and dangerous, lacking the social and legal context that promotes ethanol consumption.