Which protein is associated with obesity as a marker in the material?

• A. Adiponectin
• B. Leptin
• C. Ghrelin
• D. Resistin

Answer: (A)

Adipose tissue releases signaling proteins called adipokines that connect fat mass to metabolic health. Adiponectin is one of these adipokines with anti-inflammatory and insulin-sensitizing effects, and its level falls as body fat increases. Because lower adiponectin accompanies greater adiposity and worsened metabolic risk, it serves as a marker of obesity in the material. Leptin also rises with fat mass, but obesity often involves leptin resistance, which makes its levels a less straightforward marker. Ghrelin mainly governs hunger and isn’t a direct obesity marker, and resistin is more tied to inflammation and insulin resistance rather than a primary obesity indicator.