Which of the following is a glycopeptide hormone?

• A. FSH
• B. GH
• C. Prolactin
• D. Insulin

Answer: (A)

Glycopeptide hormones are glycoproteins, meaning they are larger peptide hormones that have carbohydrate (glycan) chains attached to their protein backbone. These carbohydrate groups help stabilize the molecule and influence its half-life and receptor interactions; many of them are formed by subunits that combine to give the final active hormone.

Follicle-stimulating hormone fits this description. It is a glycoprotein composed of two subunits (alpha and beta) with carbohydrate side chains attached to both. This glycosylation is a hallmark of this class of hormones and contributes to its stability and activity.

Growth hormone, prolactin, and insulin are peptide hormones that are not glycosylated in humans. They lack the carbohydrate attachments that define glycoprotein hormones, so they do not belong to this group.