Which Fredrickson Type corresponds to Mixed Hyperlipidemia (CM and VLDL)?

• A. Type I
• B. Type IIa
• C. Type IIb
• D. Type V

Answer: (D)

Think about which lipoproteins fail to clear and accumulate in this pattern. Fredrickson types classify hyperlipoproteinemias by the specific lipoproteins that are elevated. If both chylomicrons and VLDL are elevated, you get a mixed picture of triglyceride-rich particles from intestinal and hepatic origin. That pattern is characteristic of Type V. In contrast, Type I involves only chylomicrons, Type IIa shows only LDL elevation, and Type IIb shows LDL and VLDL but not chylomicrons. So the combination of chylomicrons and VLDL points to Type V.