Which are the metabolic functions attributed to Thyroxine in metabolism?

• A. Gluconeogenesis, Glycogenolysis, Intestinal absorption of glucose
• B. Inhibition of gluconeogenesis
• C. Lipolysis only
• D. Glycolysis suppression only

Answer: (A)

Thyroxine raises overall metabolic rate and ensures fuels are available to meet increased energy demand. In carbohydrate metabolism, it promotes glucose production and supply by stimulating liver gluconeogenesis and glycogenolysis, which release glucose into the bloodstream. It can also enhance intestinal glucose absorption, further increasing the amount of glucose that reaches circulation. Together, these actions help explain why the listed combination—gluconeogenesis, glycogenolysis, and intestinal glucose absorption—best reflects thyroxine’s metabolic effects on glucose availability.

Inhibition of gluconeogenesis would lower glucose output, which is opposite thyroxine’s action. Limiting to lipolysis or to glycolysis suppression only fails to capture the broader glucose-mobilizing effects of the hormone.