Which ALP isoenzyme resists heating at 65°C for 30 minutes?

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Multiple Choice

Which ALP isoenzyme resists heating at 65°C for 30 minutes?

Explanation:
The concept here is how different ALP isoenzymes respond to heat. Placental alkaline phosphatase is heat-stable and remains active after exposure to high temperatures, such as 65°C for 30 minutes. In contrast, the liver, bone, and intestinal isoenzymes are heat-labile and lose activity under these conditions. So if you heat a serum sample at 65°C for half an hour, the activity you’d still detect would come from the placental isoenzyme, making it the one that resists heating.

The concept here is how different ALP isoenzymes respond to heat. Placental alkaline phosphatase is heat-stable and remains active after exposure to high temperatures, such as 65°C for 30 minutes. In contrast, the liver, bone, and intestinal isoenzymes are heat-labile and lose activity under these conditions. So if you heat a serum sample at 65°C for half an hour, the activity you’d still detect would come from the placental isoenzyme, making it the one that resists heating.

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