Which Aldolase isoenzyme is found mainly in white blood cells, liver, and kidney?

• A. Aldolase B
• B. Aldolase A
• C. Aldolase C
• D. Aldolase D

Answer: (A)

Aldolase has distinct tissue-specific forms to meet different metabolic needs. The form found predominantly in liver and kidney is Aldolase B, and it is also present in leukocytes (white blood cells). This distribution fits the question’s tissues: liver and kidney are its main sites, with some activity in white blood cells. In contrast, Aldolase A is mainly in muscle and red blood cells, while Aldolase C is mainly in brain tissue. So Aldolase B is the best match for white blood cells, liver, and kidney.