What is the product of inner deiodination of T4?

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Multiple Choice

What is the product of inner deiodination of T4?

Explanation:
Inner deiodination of T4 removes the iodine from the inner ring, producing reverse T3, an inactive metabolite. Outer ring deiodination, in contrast, removes the outer-ring iodine to make T3, the active hormone. So the product of inner deiodination is reverse T3. The other options aren’t products of this pathway: TSH is a pituitary hormone, T4 is the substrate, and T3 is produced by outer ring deiodination.

Inner deiodination of T4 removes the iodine from the inner ring, producing reverse T3, an inactive metabolite. Outer ring deiodination, in contrast, removes the outer-ring iodine to make T3, the active hormone. So the product of inner deiodination is reverse T3. The other options aren’t products of this pathway: TSH is a pituitary hormone, T4 is the substrate, and T3 is produced by outer ring deiodination.

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