What is the major CK isoenzyme in skeletal muscle, constituting about 94-100%?

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Multiple Choice

What is the major CK isoenzyme in skeletal muscle, constituting about 94-100%?

Explanation:
In skeletal muscle, the dominant creatine kinase isoenzyme is CK-MM because muscle fibers primarily express the MM isoform, which efficiently regenerates ATP from phosphocreatine during contraction. This CK-MM form accounts for roughly 94–100% of the CK activity in skeletal muscle. The CK-MB isoenzyme is mainly cardiac, contributing only a small amount in skeletal muscle, and CK-BB is predominantly found in brain tissue, not muscle. So CK-MM is the major isoenzyme in skeletal muscle.

In skeletal muscle, the dominant creatine kinase isoenzyme is CK-MM because muscle fibers primarily express the MM isoform, which efficiently regenerates ATP from phosphocreatine during contraction. This CK-MM form accounts for roughly 94–100% of the CK activity in skeletal muscle. The CK-MB isoenzyme is mainly cardiac, contributing only a small amount in skeletal muscle, and CK-BB is predominantly found in brain tissue, not muscle. So CK-MM is the major isoenzyme in skeletal muscle.

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