In ultracentrifugation, which lipoprotein resides in the topmost layer?

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Multiple Choice

In ultracentrifugation, which lipoprotein resides in the topmost layer?

Explanation:
In ultracentrifugation, lipoproteins separate by density, so the least dense particles float to the top. Chylomicrons are the least dense lipoproteins, rich in triglycerides, with a density below about 0.95 g/mL. Because of their very low density, they rise to the top layer in a density gradient. In contrast, VLDL, LDL, and HDL have progressively higher densities (roughly 0.95–1.006, 1.019–1.063, and 1.063–1.21 g/mL, respectively) and sediment lower down. Therefore, the topmost layer contains chylomicrons.

In ultracentrifugation, lipoproteins separate by density, so the least dense particles float to the top. Chylomicrons are the least dense lipoproteins, rich in triglycerides, with a density below about 0.95 g/mL. Because of their very low density, they rise to the top layer in a density gradient. In contrast, VLDL, LDL, and HDL have progressively higher densities (roughly 0.95–1.006, 1.019–1.063, and 1.063–1.21 g/mL, respectively) and sediment lower down. Therefore, the topmost layer contains chylomicrons.

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