In the 1-step GDM diagnostic method using a 75 g load, what are the thresholds for fasting, 1-hour, and 2-hour glucose?

• A. FPG ≥92 mg/dL; 1h PG ≥180 mg/dL; 2h PG ≥153 mg/dL
• B. FPG ≥95 mg/dL; 1h PG ≥180 mg/dL; 2h PG ≥140 mg/dL
• C. FPG ≥90 mg/dL; 1h PG ≥170 mg/dL; 2h PG ≥160 mg/dL
• D. FPG ≥92 mg/dL; 1h PG ≥180 mg/dL; 2h PG ≥160 mg/dL

Answer: (A)

In the 1-step GDM approach with a 75 g oral glucose load, any one of these values above its threshold diagnostic criteria: fasting glucose ≥92 mg/dL, 1-hour glucose ≥180 mg/dL, or 2-hour glucose ≥153 mg/dL. These thresholds come from the IADPSG criteria and are used to identify pregnancy-glucose intolerance that raises perinatal risk. Since a single abnormal value is enough to diagnose GDM in this method, meeting any one of these cutoffs confirms GDM.

For context, the other sets of numbers reflect older or different testing strategies (such as the 3-hour 100 g OGTT used in two-step approaches) that typically require multiple abnormal values rather than just one. The key point here is the 75 g one-step thresholds: 92, 180, and 153 mg/dL.