In electrophoresis, B-VLDL travels with which lipoprotein?

• A. VLDL
• B. LDL
• C. HDL
• D. Lp(a)

Answer: (A)

In electrophoresis, lipoproteins separate mainly by their surface apolipoprotein composition and lipid content, which determines their charge and mobility. VLDL particles are large, triglyceride-rich, and tend to migrate in the region associated with the pre-beta/lipid-poor area, while LDL and other beta-lipoproteins move toward the beta region, and HDL moves toward the alpha region.

B-VLDL is a form of VLDL that, in this context, co-migrates with the VLDL fraction. That means its electrophoretic mobility matches that of VLDL rather than LDL or HDL, so it travels with VLDL. The other lipoproteins—LDL (beta-lipoprotein), HDL (alpha-lipoprotein), and Lp(a) (which often bands with LDL)—do not share this same migration pattern in this setup.