Hypoprogesteronemia is associated with which outcome?

• A. Abortion
• B. Ectopic pregnancy
• C. Prolonged pregnancy
• D. Postpartum hemorrhage

Answer: (A)

Progesterone is crucial for sustaining early pregnancy by preparing and maintaining the endometrium and by keeping the uterus quiet, reducing contractions. When progesterone levels are too low, the uterine lining can’t be kept in a supportive state and the pregnancy cannot be maintained, leading to spontaneous abortion. This is the most direct and expected outcome of hypoprogesteronemia in early pregnancy.

The other options aren’t as directly tied to low progesterone. An ectopic pregnancy can occur with normal or unknown progesterone levels and isn’t caused by a failure of luteal progesterone support. Prolonged (post-term) pregnancy and postpartum hemorrhage relate to later pregnancy/ delivery processes rather than a failure of hormonal support to sustain early pregnancy.